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M-CSF from rat

品牌
Sigma-Aldrich
货号
SRP3247
规格纯度
recombinant, expressed inE. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
价格
4312.08 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
M-CSF from rat
MGI-IM
CSF-1
Macrophage Colony Stimulating Factor
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Macrophage colony stimulating factor (M-CSF) is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts.The gene encoding this protein is localized on rat chromosome 2q34. The human protein is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant rat M-CSF is a 36.2kDa homodimeric protein containing two 155 amino acid polypeptide subunits.

生化/生理作用

Macrophage colony stimulating factor (M-CSF) is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation.

序列

MEVSEHCSHM IGNGHLQILQ QLIDSQMETA CLIEYKFVDQ EQLDDPVCYL KKAFVLVQVI IEETMRFKDN TPNANATERL QELSMKLNSC FIKDYKEQNE ACVQTYKESP LRLLEKIKNF FNETKNFLEK DWNIFSKNCN DSLAKCSSRD VVTKP

外形

Lyophilized from 5 mM Sodium Phosphate, pH 7.5.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 rat
重组 expressed inE. coli
测定 ≥98% (HPLC)
≥98% (SDS-PAGE)
形式 lyophilized
效能 ≤5.0 ng/mL ED50
分子量 18.1 kDa
包装 pkg of 10 μg
technique(s) cell culture | mammalian: suitable
杂质 <0.2 EU/μg endotoxin, tested
颜色 white to off-white
UniProt登记号 Q8JZQ0
运输 wet ice
储存温度 ?20℃
Gene Information rat ... CSF1(78965)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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