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IL-24 human

品牌
Sigma-Aldrich
货号
SRP3286
规格纯度
recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)
价格
4234.11 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
IL-24 human
MDA-7
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

IL-24 is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation.

生化/生理作用

IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.

外形

Lyophilized from 10 mM Sodium Phosphate, pH 7.5.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed in CHO cells
测定 ≥95% (HPLC)
≥95% (SDS-PAGE)
形式 lyophilized
分子量 18.9 kDa
包装 pkg of 20 μg
杂质 <0.1 EU/μg endotoxin, tested
颜色 white to off-white
UniProt登记号 Q13007
运输 wet ice
储存温度 ?20℃
Gene Information human ... IL24(11009)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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