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Anti-RAS antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4301113
规格纯度
affinity isolated antibody
价格
5097.31 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-RAS antibody produced in rabbit
HAMSV
HRAS1
CTLO
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
K-RAS
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Ras is a proto-oncogene and the gene encoding it is localized on human chromosome 11p15.5. It is a 21 kDa protein and is part of the small GTP-binding proteins superfamily.

特异性

The antibody detects endogenous level of total RAS protein.

免疫原

Synthetic peptide corresponding to a region derived from 60-74 amino acids of Human v-Ha-ras Harvey rat sarcoma viral oncogene homolog

生化/生理作用

Ras is a guanine-nucleotide binding protein that couples tyrosine kinase receptor signals to mitogen activated protein (MAP) kinase cascade. It has an important role in cell growth. Ras is a substrate for farnesyltransferase (FTase) and when farnesylated, it is anchored to the membrane. Membrane localization of Ras is crucial for its cellular activity. Inhibition of Ras farnesylation is a target for anti-cancer drug development.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 21 kDa
species reactivity rat, mouse, human
浓度 0.7 mg/mL
technique(s) western blot: 1:200-1:1000 (Cell Lysate)
同位素/亚型 IgG
登记号 NP_001123914.1
UniProt登记号 P01112
运输 wet ice
储存温度 ?20℃
Gene Information human ... HRAS(3265)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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