半岛bd体育手机客户端 说明
免疫原
Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y), according to the protein PIK3R1.
特点和优势
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目标描述
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. /Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
MDL编号 | MFCD00282407 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~85 kDa |
species reactivity | mouse, rat, human |
浓度 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
同位素/亚型 | IgG |
免疫原序列 | (L-YP-E-E-Y) |
NCBI登记号 | NP_001107644.1 NP_005018.1 NP_852556.2 |
UniProt登记号 | P27986 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... PIK3R1(5295) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich