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位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-PGR (pSer190) antibody produced in rabbit

Anti-phospho-PGR (pSer190) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300056
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-phospho-PGR (pSer 190) antibody produced in rabbit
Anti-PR antibody produced in rabbit
Anti-Progesterone receptor antibody produced in rabbit
Anti-NR3C3 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Peptide sequence around phosphorylation site of serine 190 (G-L-S(p)-P-A), according to the protein PGR.

特点和优势

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目标描述

Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid,glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition,progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

基本信息

MDL编号 MFCD00239723
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 ~99 kDa
species reactivity human
浓度 1 mg/mL
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同位素/亚型 IgG
免疫原序列 (G-L-SP-P-A)
NCBI登记号 NP_000917.3
UniProt登记号 P06401
运输 wet ice
储存温度 ?20℃
Gene Information human ... PGR(5241)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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