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位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-p38 MAPK (pTyr322) antibody produced in rabbit

Anti-phospho-p38 MAPK (pTyr322) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4504094
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-phospho-p38 MAPK (pTyr 322) antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

MAPK14 (mitogen-activated protein kinase 14) is a Ser/Thr kinase made of 90 to 360 residues. p38αMAPK is ubiquitously expressed. It is found in the cytosol, but it can translocate to the nucleus. This gene is located on human chromosome 6p21.31.

免疫原

The antiserum was produced against synthesized peptide derived from human p38 MAPK around the phosphorylation site of Tyr322.

Immunogen Range:288-337

生化/生理作用

MAPK14 (mitogen-activated protein kinase 14) participates in resistance of colon cancer cells to camptothecin-related drugs. This protein is required for the growth of embryos. This gene controls proliferation, differentiation, cell death, adhesion, migration, as well as the response to stress and many metabolic pathways. Polymorphism in MAPK14/p38a leads to deletion or overproduction of myelosuppressive cytokines and result in certain bone marrow failure syndromes.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 41 kDa
species reactivity human, mouse, rat
浓度 ~1 mg/mL
technique(s) ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号 Q16539
UniProt登记号 Q16539
运输 wet ice
储存温度 ?20℃
Gene Information human ... MAPK14(1432)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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