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位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-Met (pTyr1349) antibody produced in rabbit

Anti-phospho-Met (pTyr1349) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300190
规格纯度
affinity isolated antibody
价格
4618.16 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-phospho-Met (pTyr 1349) antibody produced in rabbit
Anti-c-Met antibody produced in rabbit
Anti-HGFR antibody produced in rabbit
Anti-RCCP2 antibody produced in rabbit
Anti-met proto-oncogene (hepatocyte growth factor receptor) antibody produced in rabbit
Anti-AUTS9 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Mesenchymal epithelial transition (MET) is a proto oncogene, mapped to human chromosome 7q21–q31. The encode protein is a transmembrane receptor tyrosine kinase (RTK) and is activated by an endogenous ligand, scatter factor or hepatocyte growth factor (HGF).

免疫原

Peptide sequence around phosphorylation site of tyrosine 1349 (E-H-Y(p)-V-H), according to the protein MET.

生化/生理作用

Mesenchymal epithelial transition (MET) facilitates wound healing and hepatic regeneration, with vital roles in embryonic, neuronal and muscle development.Mutations in the gene leads to non-small cell lung cancer (NSCLC). Copy number (GCN) of c-MET acts as a potential marker to determine poor prognosis in ovarian carcinoma patients. Binding of hepatocyte growth factor (HGF) to MET activates downstream signaling of various pathway, including mitogen-activated protein kinase (MAPK), phosphoinositide 3-kinase (PI3K)/AKT (protein kinase B), signal transducer and activator of transcription proteins, and nuclear factor-κB.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD01633070
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 ~156 kDa
species reactivity human, mouse, rat
浓度 1 mg/mL
technique(s) western blot: 1:500-1:1000
同位素/亚型 IgG
免疫原序列 (E-H-YP-V-H)
NCBI登记号 NP_000236.2
UniProt登记号 P08581
运输 wet ice
储存温度 ?20℃
Gene Information human ... MET(4233)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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