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位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-MEK1/2 (pSer221) antibody produced in rabbit

Anti-phospho-MEK1/2 (pSer221) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4504467
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-phospho-MEK1/2 (pSer 221) antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

The antiserum was produced against synthesized peptide derived from human MEK1/2 around the phosphorylation site of Ser221.

Immunogen Range:193-242

生化/生理作用

MAP2k1/2 (dual specificity mitogen-activated protein kinase kinase 1/2) is a serine threonine kinase and is required for ERK (extracellular-signal-regulated kinase) activation. Activation of ERK is associated with production of IL-10 (interleukin 10) and IL-12. Absence of the Map2k1 gene results in embryonic lethality. Map2k1 is responsible for the stimulation of epidermal proliferation, regulating cell migration in fibroblasts. Deficiency of Map2k1 protein causes lupus-like syndrome. The gene encoding Map2k1 is localized on human chromosome 15q22.31 and the MAP2K2 gene is localized on human chromosome 19p13.3.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 43 kDa
species reactivity human, rat, mouse
浓度 ~1 mg/mL
technique(s) ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号 P36507
Q02750
UniProt登记号 P36507
运输 wet ice
储存温度 ?20℃
Gene Information human ... MAP2K1(5604), MAP2K2(5605)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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