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位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-GATA1 (pSer310) antibody produced in rabbit

Anti-phospho-GATA1 (pSer310) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300031
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-phospho-GATA1 (pSer 310) antibody produced in rabbit
Anti-NFE1 antibody produced in rabbit
Anti-ERYF1 antibody produced in rabbit
Anti-GF-1 antibody produced in rabbit
Anti-GATA binding protein 1 (globin transcription factor 1) antibody produced in rabbit
Anti-GF1 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

GATA binding protein 1 (GATA1) is a key hematopoietic transcription factor. It is encoded by the gene mapped to human chromosome Xp11.23 and it belongs to the GATA transcription factor family.

免疫原

Peptide sequence around phosphorylation site of serine 310 (K-A-S(p)-G-K), according to the protein GATA1.

生化/生理作用

GATA binding protein 1 (GATA1) plays a crucial role in erythroid and megakaryocyte differentiation and proliferation. It modulates the expression of genes and acts as an E-cadherin repressor. Mutations in the GATA1 gene have been linked to transient abnormal myelopoiesis (TAM) and myeloid leukemia of DS (ML-DS). The protein has anti-apoptotic functions in breast cancer.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD02096392
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 ~43 kDa
species reactivity human, rat, mouse
浓度 1 mg/mL
technique(s) indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同位素/亚型 IgG
免疫原序列 (K-A-SP-G-K)
NCBI登记号 NP_002040.1
UniProt登记号 P15976
运输 wet ice
储存温度 ?20℃
Gene Information human ... GATA1(2623)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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