Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1

半岛bd体育手机客户端 说明

一般描述

Signal transducer and activator of transcription 6 (STAT6) transduces signals from extracellular cytokines during adaptive immunity and has recently been found to be important in the innate immune response to viral infection. STAT6 is also involved in the attenuation of the Th1 and Th17 in the nephritogenic immune response. The consequence of STAT6 activity has been associated with the pathogenesis of autoimmune disease and has been found to be actively imported to the nucleus.

特异性

This antibody recognizes STAT6 phosphorylated at (Tyr641).

免疫原

KLH-conjugated linear peptide corresponding to human STAT6 phosphorylated at (Tyr641).
Epitope: Phosphorylated (Tyr641)

应用

Research Sub Category
Transcription Factors
Flow Cytometry Analysis: 2 ?g/mL from a representative lot detected STAT6 in human peripheral blood leukocytes.
Research Category
Epigenetics & Nuclear Function
Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1 is a mouse monoclonal antibody for detection of phospho STAT6 (Tyr641) also known as Signal transducer & activator of transcription 6, IL-4 Stat & has been validated in WB, FC.

质量

Evaluated by Western Blot in NIH/3T3 cell lysates treated and untreated with PDGF.

Western Blot Analysis: 0.5 ?g/mL of this antibody detected STAT6 on 10 ?g of PDGF untreated and treated NIH/3T3 cell lysates.

目标描述

~165 kDa observed

外形

Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
NIH/3T3 cell lysates treated and untreated with PDGF

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	19E2.1, monoclonal
species reactivity	human, mouse
technique(s)	flow cytometry: suitable western blot: suitable
同位素/亚型	IgG2aκ
NCBI登记号	NP_001171549
UniProt登记号	P42226
运输	wet ice
Gene Information	human ... STAT6(6778)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable