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Anti- p38 MAPK antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701066
包装型号
规格纯度
价格
4668.88 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti- p38 MAPK antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human p38 MAPK (NP_620581.1).

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 polyclonal
形式 liquid
species reactivity rat, human, mouse
浓度 2.08 mg/mL
technique(s) immunohistochemistry: 1:50-1:200
western blot: 1:500-1:1000
UniProt登记号 Q16539
运输 wet ice
储存温度 ?20℃
Gene Information human ... MAPK14(1432)

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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