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位置: 首页> 品牌> Sigma-Aldrich> Anti-P40 Antibody, clone 11F12.1

Anti-P40 Antibody, clone 11F12.1

品牌
Sigma-Aldrich
货号
MABS519
规格纯度
clone 11F12.1, from mouse
价格
5520.38 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-P40 Antibody, clone 11F12.1
Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

P40, also known as Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor , KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, or p51, and encoded by the gene TP63/KET/P63/P73H/P73L/TP73L, is a transcriptional activator or repressor depending upon the target gene and the isoform involved. P40 has multiple isoforms. P40 is involved in Notch signaling and plays a role in p53/TP53 dependent apoptosis and epithelial morphogenesis. Moreover P40, developmentally, is required for proper limb formation. P40 is widely expressed in the adult and during development. Some isoforms, such as isoform 10 are primarily expressed in cancerous tissues while others are found only in normal tissues. Mutations in P40 lead to a variety of dysplasias and malformations, including Acro-dermato-ungual-lacrimal-tooth syndrome and Ankyloblepharon-ectodermal defects cleft lip/palate disorder and several more tragic disfiguring syndromes.

免疫原

KLH-conjugated linear peptide corresponding to human P40.

应用

Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected P40 in human prostate and human kidney tissue.
Research Category
Signaling
Research Sub Category
Signaling Neuroscience
Anti-P40 Antibody, clone 11F12.1 is an antibody against P40 for use in IHC (Paraffin) & western blotting.

质量

Evaluated by Western Blotting in SK-OV-3 cell lysate.

Western Blotting Analysis: 2.0 ?g/mL of this antibody detected P40 in 10 ?g of SK-OV-3 cell lysate.

目标描述

~40 kDa observed

外形

Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 11F12.1, monoclonal
species reactivity human
technique(s) immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型 IgG2aκ
NCBI登记号 NP_001108450
UniProt登记号 Q9H3D4
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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