您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Anti-MATK Antibody, clone 9D7

Anti-MATK Antibody, clone 9D7

品牌
Sigma-Aldrich
货号
MABC682
规格纯度
ascites fluid, clone 9D7, from mouse
价格
5854.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-MATK Antibody, clone 9D7
Megakaryocyte-associated tyrosine-protein kinase, CSK homologous kinase, CHK, Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTK
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Megakaryocyte-associated tyrosine-protein kinase (MATK), or alternatively CSK homologous kinase (CHK), Hematopoietic consensus tyrosine-lacking kinase, Protein kinase HYL, Tyrosine-protein kinase CTK, is an important kinase in hematopoietic signal transduction in blood cells as well as in other cells such as neurons and T cells. As its name would imply, MATK was first associated with megakaryocytes, the cells that give rise to platelets. MATK is able to phosphorylate and inactivate Src family kinases and may play a role in the regulation of proliferation of some cells such as T cells. In the nervous system MATK (called CHK in the older literature) plays a distinct role in the development of the CNS. MATK was found to be expressed in a developmental manner and expressed not only in developing neurons but also astrocytes and oligodendrocytes, but not in any of the associated tumors from these cell types, possibly indicating that it is the loss of expression of MATK activity that impacts tumorigenesis. EMD-Millipore’s Anti-MATK monoclonal antibody has been tested in western blot using K562 cell lysates and in flow cytometry using permeabilized K562 cells in culture.

免疫原

Purified recombinant fragment of human MATK expressed in E. Coli.

应用

Research Sub Category
Apoptosis - Additional
Research Category
Apoptosis & Cancer
Detect Megakaryocyte-associated tyrosine-protein kinase using this mouse monoclonal antibody, Anti-MATK Antibody, clone 9D7 validated for use in western blotting & Flow Cytometry.
Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected MATK in K562 cells.

Optimal working dilutions must be determined by end user.

质量

Evaluated by Western Blotting in K562 cell lysate.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected MATK in K562 cell lysate.

目标描述

~56 kDa observed. Uncharacterized bands may appear in some lysate(s).

外形

Purified mouse monoclonal liquid in PBS containing up to 0.1% sodium azide and 50% glycerol.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

分析说明

Control
K562 cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 ascites fluid
antibody product type primary antibodies
克隆 9D7, monoclonal
species reactivity human
technique(s) flow cytometry: suitable
western blot: suitable
同位素/亚型 IgG1
UniProt登记号 P42679
运输 wet ice

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 2

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map