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Anti-GLP1R antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4501220
规格纯度
affinity isolated antibody
价格
5323.87 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-GLP1R antibody produced in rabbit
GLP1R
GLP-1R
GLP-1-R
GLP-1 receptor
Glucagon-like peptide 1 receptor
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Glucagon-like peptide 1 receptor (GLP1R) protein belongs to the class B G protein-coupled receptor (GPCR) secretin family. This classic seven-transmembrane protein is abundantly expressed in the cardiovascular system. The GLP1R gene is located on the human chromosome 6p21. Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.
Anti-GLP1R Antibody detects endogenous levels of total GLP1R protein.

免疫原

The antiserum was produced against synthesized peptide derived from human GLP1R.

Immunogen Range:101-150

应用

Anti-GLP1R antibody produced in rabbit has been used in immunofluorescence staining.

生化/生理作用

Glucagon-like peptide 1 receptor (GLP1R) protein participates in the activation of protein kinase A (PKA), phosphoinositide 3-kinase (PI3K), MEK1/2, and endothelial nitric oxide synthase (eNOS) pathways. Hence, it plays a key role in apoptosis reduction, improved energy metabolism, decreased inflammation in myocardial cells, and vasodilation in myocardial arteries. The large N-terminal extracellular domain of GLP1R participates in ligand binding. Alterations in the GLP1R gene might increase the risk of coronary artery disease (CAD).

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 53 kDa
species reactivity mouse, human
浓度 ~1 mg/mL
technique(s) ELISA: 1:5000
immunofluorescence: 1:100-1:500
NCBI登记号 P43220
UniProt登记号 P43220
运输 wet ice
储存温度 ?20℃
Gene Information human ... GLP1R(2740)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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