Anti-FLT4 antibody produced in rabbit

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一般描述

Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3.

免疫原

Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4.

应用

Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry.

生化/生理作用

Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease.

特点和优势

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目标描述

Receptor for VEGFC. Has a tyrosine-protein kinase activity.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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