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Anti-FGFR1 (Ab-154) antibody produced in rabbit

抗-FGFR1 (Ab-154) 兔抗

品牌
Sigma-Aldrich
货号
SAB4300488
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
服务
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  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-FGFR1 (Ab-154) antibody produced in rabbit
Anti-BFGFR antibody produced in rabbit
Anti-FGFBR antibody produced in rabbit
Anti-fibroblast growth factor receptor 1 antibody produced in rabbit
Anti-CD331 antibody produced in rabbit
Anti-CEK antibody produced in rabbit
抗-FGFR1 (Ab-154) 兔抗
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

FGFR1 (fibroblast growth factor receptor 1) gene codes for 9 isoforms of FGFR1. It has 19 exons spanning 55kb DNA. It is located on human chromosome 8p11.1. High level expression of FGFR1 is seen in midfacial membranous ossification sites. It is mostly present in neurons like hippocampal and dentate gyrus neurons.

免疫原

Peptide sequence around aa. 152-156 (A-P-Y-W-T), according to the protein FGFR1.

应用

Anti-FGFR1 (Ab-154) antibody has been used in western blotting .

生化/生理作用

FGFR1 (fibroblast growth factor receptor 1) helps in the growth of nervous system. It also controls the skeletal development and bone homeostasis. FGFR1 mutations lead to craniosynostosis and facial abnormalities. Mutation in FGFR1 Ig-like domain II-III linker region (FGFR1 P252R) results in Pfeiffer syndrome.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

FGF encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 ~145 kDa
species reactivity human, mouse
浓度 1 mg/mL
technique(s) western blot: 1:500-1:1000
同位素/亚型 IgG
免疫原序列 (A-P-Y-W-T)
NCBI登记号 NP_001167534.1
UniProt登记号 P11362
运输 wet ice
储存温度 ?20℃
Gene Information human ... FGFR1(2260)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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