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Anti-EPOR antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2100693
规格纯度
affinity isolated antibody
价格
6262.8 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-EPOR antibody produced in rabbit
Anti-erythropoietin receptor
Anti-MGC138358
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the N terminal region of human EPOR

应用

Anti-EPOR antibody produced in rabbit has been used in immunoblot analysis and magnetic cell sorting.

生化/生理作用

The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

序列

Synthetic peptide located within the following region: DHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD01092334
PubChem化学物质编号 329824639

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 53 kDa
species reactivity dog, human, mouse, rat
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
UniProt登记号 P19235
运输 wet ice
储存温度 ?20℃
InChI 1S/C40H74O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(41)43-40(42)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20H,3-16,21-38H2,1-2H3/b19-17-,20-18-
InChI key QLXNJYBNAORLFC-CLFAGFIQSA-N
Gene Information human ... EPOR(2057)

Sigma-Aldrich

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