Anti-Cytokeratin 18 Antibody, clone RCK106

半岛bd体育手机客户端 说明

一般描述

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight from between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8, The individual cytokeratin polypeptides are designated 1-20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies.

特异性

Cytokeratin 18. MAB3236 reacts exclusively with human glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells as well as adenocarcinomas originating from them.

SPECIES REACTIVITY:

Human only. Does not react with other species.

免疫原

Cytoskeletal preparation of human bladder carcinoma cell line T24.

应用

Research Category
Cell Structure
Anti-Cytokeratin 18 Antibody, clone RCK106 detects level of Cytokeratin 18 & has been published & validated for use in FC, WB, IC, IH(P).
Research Sub Category
Cytokeratins
Western blot

Immunohistochemistry on frozen and paraffin embedded tissue sections.

Immunocytochemistry

Flow cytometry

Optimal working dilutions must be determined by the end user.

联系

Replaces: 04-586

外形

Format: Purified
Liquid in buffer with 0.1% sodium azide.

储存及稳定性

Maintain at -20°C in undiluted aliquots up to 6 months. Avoid repeated freeze/thaw cycles.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	RCK106, monoclonal
species reactivity	human
manufacturer/tradename	Chemicon?
technique(s)	flow cytometry: suitable immunocytochemistry: suitable immunohistochemistry: suitable (paraffin) western blot: suitable
同位素/亚型	IgG1
NCBI登记号	NM_000224.2 NM_199187.1
UniProt登记号	P05783
运输	dry ice
Gene Information	human ... KRT18(3875)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable