Anti-CYCLIN D1, C-Terminal antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

The CCND1 (cyclin D1) gene is mapped to human chromosome 11q13.3.
Anti-CYCLIN D1 antibody detects endogenous levels of total CYCLIN D1 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human Cyclin D1.

Immunogen Range:246-295

应用

Anti-CYCLIN D1, C-Terminal antibody produced in rabbit has been used in western blotting analysis.

生化/生理作用

CCND1 (cyclin D1) regulates cell cycle by mediating the G1 to S phase transition. The gene gets activated by β-catenin and participates in the process of tumor formation. Upregulation of the gene is observed in cancer such as lung, breast, colon, hematopoietic and prostate carcinomas, and promotes contact independent cell growth. Variation in CCND1 contributes to increased occurrence of colorectal cancer.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00239664
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 33 kDa
species reactivity	rat, mouse, human
浓度	~1 mg/mL
technique(s)	ELISA: 1:5000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000
NCBI登记号	P24385
UniProt登记号	P24385
运输	wet ice
储存温度	?20℃
Gene Information	human ... CCND1(595)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable