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Anti-CSK antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4500507
规格纯度
affinity isolated antibody
价格
4618.16 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-CSK antibody produced in rabbit
C-SRC kinase
Protein-tyrosine kinase CYL
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The C-terminal Src kinase (CSK) gene is mapped to human chromosome 15q24.1. Anti-CSK Antibody detects endogenous levels of total CSK protein.

免疫原

The antiserum was produced against synthesized peptide derived from human CSK.

Immunogen Range:31-80

生化/生理作用

C-terminal Src kinase (CSK) is known to support dengue virus replication. CSK negatively controls Src, an oncogenic protein found to be upregulated in various types of cancer. CSK is responsible for Src phosphorylation at tyrosine 530, which inhibits its activity. It controls immune response, by preventing T cell activation through its association with lymphoid-specific phosphatase. CSK possesses SH2 domain, a regulatory domain that mediates its binding to scaffold proteins for membrane translocation. This regulation is known to elevate CSK′s activity.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 50 kDa
species reactivity human, mouse, rat
浓度 ~1 mg/mL
technique(s) ELISA: 1:5000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登记号 P41240
UniProt登记号 P41240
运输 wet ice
储存温度 ?20℃
Gene Information human ... CSK(1445)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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