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Anti-CDK6 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700113
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-CDK6 antibody produced in rabbit
CDK6
MCPH12
PLSTIRE
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human CDK6 (NP_001250.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 36
species reactivity human, mouse
浓度 1.15 mg/ml
technique(s) immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
immunoprecipitation (IP): 1:50-1:100
western blot: 1:500-1:2000
UniProt登记号 Q00534
运输 wet ice
储存温度 ?20℃
Gene Information human ... CDK6(1021)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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