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Anti-Caspase-1 (ab2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
PRS3463
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
4731.57 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Caspase-1 (ab2) antibody produced in rabbit
Anti-ICE
Anti-Caspase 1, apoptosis-related cysteine peptidase (Interleukin 1, beta, convertase)
Anti-IL-1β converting enzyme
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Caspase-1 is also known as interleukin-1βconverting enzyme (ICE). It is located on chromosome 11q22.2. It has 10 exons, an N terminal CARD (caspase activation and recruitment domain), a large P20 subunit and a small P10 subunit. It is present in leukocytes, monocytes and epithelial cells.

免疫原

a 15 amino acid peptide from near the middle of human Caspase-1.

生化/生理作用

Caspase-1 can transform the pro-inflammatory cytokines, interleukin-1β (IL-1β) and IL-18 into their active forms. It participates in pyroptosis. It is overexpressed in the aorta of coronary atherosclerosis patients.It helps in host cell survival by inducing membrane biogenesis to restore the impairment caused by pore-forming toxins.

联系

The action of this antibody can be blocked using blocking peptide SBP3463.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
technique(s) immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登记号 P29466
运输 dry ice
储存温度 ?20℃
Gene Information human ... CASP1(834)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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