半岛bd体育手机客户端 说明
一般描述
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac.
免疫原
BCR (NP_004318, 52-86)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BCR.
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
基本信息
MDL编号 | MFCD02686065 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | saturated ammonium sulfate (SAS) precipitated |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | human |
technique(s) | indirect ELISA: 1:1000 |
NCBI登记号 | NP_004318 |
UniProt登记号 | P11274 |
运输 | dry ice |
储存温度 | ?20℃ |
Gene Information | human ... BCR(613) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich