Anti-Bax antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

BCL2 associated X, apoptosis regulator (BAX) is a proapoptotic protein of the B-cell lymphoma 2 (BCL2) protein family. The gene encoding it is localized on human chromosome 19q13.33.

免疫原

Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax.

应用

Anti-Bax antibody produced in rabbit has been used in Western blotting.

生化/生理作用

BCL2 associated X, apoptosis regulator (BAX) forms a heterodimer with B-cell lymphoma 2 (BCL2) and functions as an apoptotic activator. BAX interacts with and increases the opening of the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in the mitochondrial membrane potential and the release of cytochrome c. The expression of BAX gene is regulated by the tumor suppressor p53 and BAX has been shown to be involved in p53-mediated apoptosis.

特点和优势

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联系

The action of this antibody can be blocked using blocking peptide SBP3500343.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00282585
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	immunocytochemistry: suitable immunofluorescence: suitable immunoprecipitation (IP): suitable indirect ELISA: suitable western blot: suitable
NCBI登记号	AAA03619
UniProt登记号	Q07812
运输	dry ice
储存温度	?20℃
Gene Information	human ... BAX(581)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable