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Anti-ADRB2 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1405433
规格纯度
purified immunoglobulin, buffered aqueous solution
价格
4618.16 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-ADRB2 antibody produced in mouse
B2AR
ADRB2R
ADRBR
BAR
BETA2AR
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes β-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. (provided by RefSeq)
The gene encoding β-2-adrenergic receptor (ADRB2) is localized on human chromosome 5q32. ADRB2 is a seven-transmembrane receptor.

免疫原

ADRB2 (NP_000015, 1 a.a. ~ 413 a.a) full-length human protein.

Sequence
MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL

生化/生理作用

The beta-2-adrenergic receptor (ADRB2) functions in response to adrenaline and noradrenaline. The ADRB2 pathway has been associated with various cancers like that of the breast, stomach and prostate.

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~46.6 kDa
species reactivity human
technique(s) flow cytometry: suitable
western blot: 1 μg/mL
NCBI登记号 NM_000024
UniProt登记号 P07550
运输 dry ice
储存温度 ?20℃
Gene Information human ... ADRB2(154)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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