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4-1BBL human

品牌
Sigma-Aldrich
货号
SRP3002
规格纯度
recombinant, expressed inE. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
价格
4662.37 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
4-1BBL human
CD137L
TNFSF9
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. 4-1BBL binds to its receptor 4-1BB, and provides a co-stimulatory signal for T cell activation and expansion. The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 205 amino acid extracellular domain. The soluble form of 4-1BL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.

生化/生理作用

4-1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and macrophages. The soluble form of 4-1BBL contains the TNF-like portion of the extracellular domain of 4-1BBL. Recombinant human 4-1BBL is a soluble 19.5 kDa protein consisting of 185 amino acid residues.

序列

MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE

外形

Lyophilized from 5 mM Tris, pH 8.0 + 75 mM NaCl.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

生物来源 human
重组 expressed inE. coli
测定 ≥98% (HPLC)
≥98% (SDS-PAGE)
形式 lyophilized
效能 5-10 ng/mL ED50
分子量 19.5 kDa
包装 pkg of 20 μg
technique(s) cell culture | mammalian: suitable
杂质 <0.1 EU/μg endotoxin, tested
颜色 white to off-white
UniProt登记号 P41273
运输 wet ice
储存温度 ?20℃
Gene Information human ... TNFSF9(8744)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H315 - H319
预防措施声明 P305 + P351 + P338
危险分类 Eye Irrit. 2 - Skin Irrit. 2
储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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