半岛bd体育手机客户端 说明
一般描述
UbcH7 is a class I enzyme which functions in the stress response and the control of transcription factors. The enzyme is ubiquitously expressed with high levels of expression seen in adult muscle. It has been demonstrated to participate in the ubiquitinylation of p53, c-Fos and NF-κB. UbcH7 is one of two E2s (UbcH5 being the other) with which HECT domain proteins interact with UbcH7 being able to efficiently substitute for UbcH5 in E6-AP-dependent ubiquitinylation. Typical enzyme concentration to support conjugation in vitro is 100nM to 1μM depending upon conditions.
Product Source: Recombinant human UbcH7 Conjugating Enzyme expressed inE. coli.
外形
Purified using Ni2+chelation chromatography with Ni2+ in limiting concentration.
储存及稳定性
Stable for 1 year at -80°C from date of shipment. Avoid multiple freeze/thaw cycles. After initial defrost, aliquot into individual tubes and refreeze at -80°C.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160405 |
| NACRES | NA.32 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 生物来源 | human |
| 测定 | >95% (SDS-PAGE) |
| 分子量 | Mw18 kDa |
| manufacturer/tradename | Upstate? |
| NCBI登记号 | NM_003343.4 NM_182688.1 |
| UniProt登记号 | P60604 |
| 运输 | dry ice |
| Gene Information | human ... UBE2G2(7327) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
