Anti-Rac1 Antibody, clone 23A8, Magnetic bead Conjugate

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一般描述

Rac1 is a member of a RhoGTPase subfamily (Rac1-Rac4) that transduces extracellular signals from G-coupled protein receptors (GPCR), integrins and growth factor receptors to effector molecules that modulate multiple signaling pathways. While Rac1 supports the activation of MAPkinase pathways and gene activation, it’s most important functions include the regulation of cytoskeletal structures. Together with Rho (regulator of stress fibers) and Cdc42 (regulator of filopodia), Rac modulates the formation of focal adhesion (FA) complexes; membrane ruffles and lamellipodia that contribute to important cell functions related to cell attachment and movement.

特异性

Other species have not been tested.
Recognizes human Rac1.

应用

Anti-Rac1 Antibody, clone 23A8, Magnetic bead Conjugate detects level of Rac1 & has been published & validated for use in WB & IP.

目标描述

21 kDa

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt. DO NOT FREEZE! Wash the magnetic beads with an appropriate buffer prior to use to remove sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

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安全信息