Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Cy5 conjugate

半岛bd体育手机客户端 说明

一般描述

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure.

The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

特异性

Histone H3 phosphorylated at Ser10
Expected to cross react with all vertebrate species.

免疫原

A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3, clone 3H10. This is a Cy5 conjugate of Anti-phospho-Histone H3 (Ser10), clone 3H10, Catalog # 05-806.

应用

Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Cy5 Conjugate is a Mouse Monoclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p,
is labeled with Cy5.5 NHS ester (Cy5) and validated in IF, WB.
Research Sub Category
Histones
Research Category
Epigenetics & Nuclear Function

质量

Routinely evaluated by immunoblot in acid extrated protein from mitotic HeLa cells treated with colcemid (17-306).

目标描述

17kDa

外形

Protein G Purified

储存及稳定性

1 year at 4°C from date of shipment

分析说明

Control
Acid extracts from colcemid treated HeLa cells (lane 2)

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
偶联物	CY5 conjugate
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	3H11, monoclonal
species reactivity	human
manufacturer/tradename	Upstate?
technique(s)	immunofluorescence: suitable western blot: suitable
同位素/亚型	IgG1κ
NCBI登记号	NM_003493.2
UniProt登记号	Q16695
运输	wet ice
Gene Information	human ... HIST1H3F(8968)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable