Anti-JAK1 Antibody

半岛bd体育手机客户端 说明

特异性

Recognizes JAK1 (Janus Kinase 1). The members of the JAK family of cytoplasmic protein tyrosine kinases physically associate with ligand-bound receptors. It is this association that results in tyrosine phosphorylation and activation. JAK1 is approximately 130 kDa and contains a C-terminal tyrosine kinase domain, an adjacent kinase or kinase-related domain, and five other domains that are highly conserved among JAK family members.

免疫原

Synthetic peptide corresponding to 21 amino acids of human/mouse/rat JAK1

(KTLIEKERFYESRCRPVTPS-C)

应用

Immunoprecipitation: Use at 5-10μl per 1-2mg lysate

Western blot: (1:1000-1:2000)

The amount of JAK1 in cell lines tends to be extremely low. If the signal is weak it is recommended that a RIPA cell lysate (1-2mg protein) be prepared and JAK1 be first concentrated by immunoprecipitation and then immunoblotted. A degradation product of JAK1 (~110kDa) is also detected by the antiserum in immunoblots.

Optimal working dilutions must be determined by end user.
Research Category
Signaling
Research Sub Category
Immunological Signaling
This Anti-JAK1 Antibody is validated for use in IP, WB for the detection of JAK1.

外形

Serum. Whole rabbit antiserum containing sodium azide.

储存及稳定性

Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	serum
antibody product type	primary antibodies
克隆	polyclonal
species reactivity	human, rat, mouse
manufacturer/tradename	Chemicon?
technique(s)	immunoprecipitation (IP): suitable western blot: suitable
NCBI登记号	NM_002227.2
UniProt登记号	P23458
运输	wet ice
Gene Information	human ... JAK1(3716)

安全信息

储存分类代码

10 - Combustible liquids