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Zotepine

佐替平

品牌
Sigma-Aldrich
CAS
26615-21-4
货号
Z0877
包装型号
规格纯度
价格
1027.89 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
26615-21-4
Zotepine
2-[(8-chlorodibenzo[b,f]-thiepin-10-yl)oxy]-N,N-dimethylethanamine
佐替平
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Zotepine has been used as an anti-psychotic agent:

  • in biophysical studies with serotonin 2A receptor (5-HT2AR)
  • to study its effects on the inhibition of human organic cation transporter 1 (hOCT1)
  • to study its protective effects on the human embryonic kidney (HEK cells)

包装

10, 50 mg in glass bottle

生化/生理作用

Zotepine acts as an antagonist of dopamine D1, D2, and serotonin (5-HT2A/2C) receptors, and noradrenaline transporters. It shows therapeutic effects against schizophrenia and acute mania.
Zotepine is an atypical antipsychotic.

特点和优势

This compound was developed by Astellas. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. Z0877.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式 C18H18ClNOS
分子量 331.86
MDL编号 MFCD00868143
PubChem化学物质编号 329831602
NACRES NA.77

半岛bd体育手机客户端 性质

测定 >98% (HPLC)
质量水平 100
形式 powder
颜色 white to off-white
溶解性 DMSO: ≥20 mg/mL
创始人 Astellas
储存温度 room temp
SMILES string CN(C)CCOC1=Cc2ccccc2Sc3ccc(Cl)cc13
InChI 1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
InChI key HDOZVRUNCMBHFH-UHFFFAOYSA-N

安全信息

象形图 GHS07GHS09
警示用语: Warning
危险声明 H302 - H400
预防措施声明 P273
危险分类 Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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