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Zatebradine hydrochloride

品牌
Sigma-Aldrich
CAS
91940-87-3
货号
Z0127
规格纯度
≥98% (HPLC), powder
价格
2521.28 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
91940-87-3
Zatebradine hydrochloride
7,8-Dimethoxy-3-[3-[-N-[2-(3,4 dimethoxyphenyl)ethyl]-N-methylamino]propyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride
UL-FS49
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Zatebradine hydrochloride has been used:

  • as an Ifblocker to study its effects on cardiomyocyte clusters (CMCs)
  • as a hyperpolarization-activated and cyclic nucleotide-gated (HCN) channel inhibitor to study its effects on viability of degenerating rod or cone photoreceptors in mice
  • as a bradycardiac agent to study its effects on tachycardia and elevated temperature in fish

包装

10, 50 mg in glass bottle

生化/生理作用

Zatebradine is a bradycardiac agent.
HCN channel blocker: blocker of neuronal Ih, related cardiac Ifchannels and ATP-sensitive Kirchannels.

特点和优势

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式 C26H37ClN2O5
分子量 493.04
MDL编号 MFCD06798356
PubChem化学物质编号 24724672
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 white
溶解性 H2O: >10 mg/mL
创始人 Boehringer Ingelheim
储存温度 2-8℃
SMILES string Cl[H].COc1ccc(CCN(C)CCCN2CCc3cc(OC)c(OC)cc3CC2=O)cc1OC
InChI 1S/C26H36N2O5.ClH/c1-27(13-9-19-7-8-22(30-2)23(15-19)31-3)11-6-12-28-14-10-20-16-24(32-4)25(33-5)17-21(20)18-26(28)29;/h7-8,15-17H,6,9-14,18H2,1-5H3;1H
InChI key ZRNKXJHEQKMWCH-UHFFFAOYSA-N

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

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