Wee1, active from rat

半岛bd体育手机客户端 说明

应用

Wee1, active from rat may be used to study apoptotic signaling.

生化/生理作用

Wee1 is a protein tyrosine kinase that phosphorylates Cdc2 on Tyr15 and hence inactivates the CDK1 and CDK2, which facilitates in the negative regulation of entry of cells into mitosis. Increased level of wee1 stimulates Human Immunodeficiency Virus type 1 (HIV-1) Vpr induced cell cycle arrest at G2/M transition followed by apoptosis.
Protein inhibitor of Cdk2 kinase

单位定义

One unit of Wee 1 is defined as the amount of Wee 1 which inhibits 90% of the activity of 10 units of Cdk2

外形

Solution in 50 mM Tris-HCl, pH 7.5, 1 mM EDTA, 1 mM DTT, 10% Glycerol

基本信息

MDL编号

MFCD03459055

半岛bd体育手机客户端 性质

质量水平	200
生物来源	rat
重组	expressed inE. coli
形式	solution
分子量	~110 kDa
UniProt登记号	Q63802
application(s)	cell analysis
运输	dry ice
储存温度	?70℃
Gene Information	rat ... Wee1(308937)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)