半岛bd体育手机客户端 说明
一般描述
WAY-200070 is a potent, selective estrogen receptor-beta (ER-β) agonist (IC50 2.3 nM vs. 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.
应用
WAY-200070, a selective estrogen receptor-beta (ER-β) agonist, may be used in estrogen receptor signaling research along with other ERβ agonists [diarylpropionitrile (DPN)] and antagonist to help identify and differentiate the functions of estrogen receptor-beta(s) (ER-β) involved in processes such as regulation of the physiology of the endocrine pancreas; modulation of visceral pain; and stress response. WAY-200070 may be used to help establish that an observed physiological or cell signaling response is ER-β-dependent, especially versus ERα.
包装
5, 25 mg in glass bottle
生化/生理作用
Potent, selective estrogen receptor-beta (ER-β) agonist (IC502.3 nM vs 155 nM for ER-α) with anxiolytic-like and antidepressant-like effects.
特点和优势
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C13H8BrNO3 |
| 分子量 | 306.11 |
| MDL编号 | MFCD16618385 |
| PubChem化学物质编号 | 329830426 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 溶解性 | DMSO: ≥20 mg/mL |
| 创始人 | Wyeth |
| 储存温度 | 2-8℃ |
| SMILES string | Oc1ccc(cc1)-c2nc3cc(O)cc(Br)c3o2 |
| InChI | 1S/C13H8BrNO3/c14-10-5-9(17)6-11-12(10)18-13(15-11)7-1-3-8(16)4-2-7/h1-6,16-17H |
| InChI key | BAAILVWEAXFTSF-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 - H319 |
| 预防措施声明 | P264 - P270 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313 |
| 危险分类 | Acute Tox. 3 Oral - Eye Irrit. 2 |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
