Urocortin human

半岛bd体育手机客户端 说明

Amino Acid Sequence

Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2

应用

Urocortin human can be used as a test compound for studying the impact of corticotropin-releasing factor (CRF) receptor agonist and antagonist on sleep-wake patterns in conscious rats by using radiotelemetry system.

包装

250 μg in glass bottle

生化/生理作用

Urocortin is a CRF-related neuropeptide having high affinity for CRF2 receptor possess appetite-suppressing effect. Urocortin along with corticotropin-releasing factor (CRF) binding protein (CRF-BP) enhances the free CRF levels in human brain by displacing hCRF from the binding protein.
Binds to CRF receptor types 1, 2α, and 2β; stimulates cAMP accumulation from cells transfected with these receptors. Actsin vitroto release ACTH from rat anterior pituitary cells.

基本信息

经验(实验)分子式	C204H337N63O64
分子量	4696.24
MDL编号	MFCD00802621
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	200
生物来源	human
测定	≥85% (HPLC)
形式	powder
technique(s)	ligand binding assay: suitable
UniProt登记号	P55089
储存温度	?20℃
Gene Information	human ... UCN(7349)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)