Ubiquitin-Specific Protease 8 human

半岛bd体育手机客户端 说明

一般描述

Human USP8 (Ubiquitin-Specific Protease 8) or UBPY, amino-acids 2-1118 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system.

应用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

生化/生理作用

Expression of ubiquitin-specific protease 8 (USP8) in mice is critical for proper expression and stability of several growth factor receptors including epidermal growth factor receptor. However, USP8 was shown to degrade chemokine receptor 4.

外形

Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 ng/μl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0.

半岛bd体育手机客户端 性质

质量水平	200
重组	expressed inSf9 cells
测定	≥0.10 mg/mL protein basis (Bradford) ≥70% (SDS-PAGE)
形式	buffered aqueous glycerol solution
分子量	128 kDa
NCBI登记号	NM_005154
运输	dry ice
储存温度	?70℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable