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Monoclonal Anti-USP25 antibody produced in mouse

品牌
Sigma-Aldrich
货号
U7883
规格纯度
~1.0 mg/mL, clone U25.7, purified immunoglobulin, buffered aqueous solution
价格
4731.57 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-USP25 antibody produced in mouse
Anti-Ubiquitin specific peptidase 25
Anti-USP21
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Monoclonal Anti-USP25 (mouse IgG2a isotype) is derived from the hybridoma U25.7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment of human USP25. USP25 (ubiquitin-specific protease 25) is a member of the ubiquitin processing proteases (UBP) family. It is located on the gene-poor region of 21q11.2 human chromosome.

应用

Monoclonal Anti-USP25 antibody has been used in:

  • enzyme linked immunosorbent assay (ELISA)
  • immunoblotting
  • immunocytochemistry

生化/生理作用

USP25 (ubiquitin-specific protease 25) is a target for sumoylation. It takes place within the two ubiquitin interaction motifs (UIM) of USP25 that are required for efficient hydrolysis of Ub (ubiquitin), and thus impairs USP25 activity as a result of reduced affinity to Ub chains. Overexpression of USP25 has been observed in Down syndrome fetal brain.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 U25.7, monoclonal
形式 buffered aqueous solution
分子量 antigen ~126 kDa
species reactivity human, rat, mouse
浓度 ~1.0 mg/mL
technique(s) immunocytochemistry: suitable
indirect ELISA: suitable
western blot: 1-2 μg/mL using total extract of HEK-293T cells expressing USP25.
同位素/亚型 IgG2a
UniProt登记号 Q9UHP3
运输 dry ice
储存温度 ?20℃
Gene Information human ... USP25(29761)
mouse ... Usp25(30940)
rat ... Usp25(304150)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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