半岛bd体育手机客户端 说明
应用
(?)-trans-(1S,2S)-U-50488 hydrochloride hydrate (U-50488) has been used as a κ-opioid receptor (KOR) agonist has been used to study its effect on the increase of tidal volumes in adult red-eared slider turtles (Trachemys scripta).
包装
5, 25, 100 mg in glass bottle
生化/生理作用
Potent κ opioid receptor agonist; more potent enantiomer of (±)-trans-U-50488.
制备说明
(?)-trans-(1S,2S)-U-50488 hydrochloride hydrate is soluble in water at 13 mg/ml.
基本信息
经验(实验)分子式 | C19H26Cl2N2O · HCl · xH2O |
分子量 | 405.79 (anhydrous basis) |
MDL编号 | MFCD11044455 |
PubChem化学物质编号 | 24278019 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
旋光性 | [α]22/D -39.0 to -32.0°, c = 0.5 in methanol(lit.) |
储存条件 | desiccated |
颜色 | white |
溶解性 | H2O: 13 mg/mL |
储存温度 | 2-8℃ |
SMILES string | O.Cl.CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 |
InChI | 1S/C19H26Cl2N2O.ClH.H2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;;/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H;1H2/t17-,18-;;/m0../s1 |
InChI key | UWPRPWMHQDPOFR-MPGISEFESA-N |
Gene Information | human ... OPRK1(4986) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich