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TRKA (440-end), active, GST tagged human

品牌
Sigma-Aldrich
CAS
152787-58-1
货号
T4202
规格纯度
PRECISIO?Kinase, recombinant, expressed in baculovirus infectedSf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
价格
6484.55 *本价格含增值税费
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半岛bd体育手机客户端 名称:
152787-58-1
TRKA (440-end), active, GST tagged human
TRK1
DKFZp781l14186
NTRK1
p140-TrKA
MTC
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

TRKA (440-end), active, GST tagged human was used to study functional NGF signal transduction.

生化/生理作用

TRKA (440-end), active, GST tagged human is a 140 kD membrane-spanning protein tyrosine kinase that belongs to proto-oncogene family. TRKA facilitates the regulation of cell differentiation and survival via activating SHC1 and FRS2 which in turn activates a GRB2-Ras-MAPK cascade. It also plays a pivotal role in controlling NF-κ-B activation as well as transcription of genes involved in cell survival via PLCG1.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

质量水平 200
生物来源 human
重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?Kinase
测定 ≥70% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 19-25 nmol/min·mg
分子量 ~66 kDa
technique(s) activity assay: suitable
UniProt登记号 P04629
运输 dry ice
储存温度 ?70℃
Gene Information human ... NTRK1(4914)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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