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位置: 首页> 品牌> Sigma-Aldrich> 2,4-二氨基-5-(3,4,5-三甲氧基苄基)嘧啶 乳酸盐

Trimethoprim lactate salt

甲氧苄啶 乳酸盐

品牌
Sigma-Aldrich
CAS
23256-42-0
货号
T0667
包装型号
规格纯度
≥98%
价格
4694.34 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
23256-42-0
Trimethoprim lactate salt
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine lactate salt
甲氧苄啶 乳酸盐
2,4-二氨基-5-(3,4,5-三甲氧基苄基)嘧啶 乳酸盐
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Chemical structure: pyrimidine

应用

Trimethoprim is primarily used as an antibacterial agent. It has dihydrofolate reductase inhibitor activity with selectivity for the prokaryote enzyme. It is used clinically to treat urinary tract infections, mild acute prostatitis, recurrent cystitis, asymptomatic bacteriuria during pregnancy and respiratory tract infections. Trimethoprim lactate salt is used as a selection agent.

包装

250 mg in glass bottle

生化/生理作用

The combination of trimethoprim and sulfamethoxazole interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to prokaryote-specific dihydrofolate reductase (DHFR) and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis.

其他说明

Keep container tightly closed in a dry and well-ventilated place.

基本信息

经验(实验)分子式 C14H18N4O3· C3H6O3
分子量 380.40
EC 号 245-533-1
MDL编号 MFCD00171722
PubChem化学物质编号 329826610
NACRES NA.85

半岛bd体育手机客户端 性质

质量水平 200
测定 ≥98%
形式 powder
储存条件 (Keep container tightly closed in a dry and well-ventilated place.)
颜色 white
溶解性 H2O: soluble 20 mg/mL
作用机制 DNA synthesis | interferes
enzyme | inhibits
抗生素抗菌谱 Gram-negative bacteria
Gram-positive bacteria
mycobacteria
储存温度 2-8℃
SMILES string CC(O)C(O)=O.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
InChI 1S/C14H18N4O3.C3H6O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-2(4)3(5)6/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2,4H,1H3,(H,5,6)
InChI key IIZVTUWSIKTFKO-UHFFFAOYSA-N

安全信息

象形图 GHS06GHS08
警示用语: Danger
危险声明 H301 - H361d
预防措施声明 P202 - P264 - P270 - P280 - P301 + P310 - P405
危险分类 Acute Tox. 3 Oral - Repr. 2
储存分类代码 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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