雷尼酸锶 - 半岛电竞官方网址

雷尼酸锶

品牌

Sigma-Aldrich

CAS

135459-87-9

货号

SML0596

包装型号

规格纯度

≥98% (HPLC)

价格

572.49 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

135459-87-9
Strontium ranelate
2-[N,N-Di(carboxymethyl)amino]-3-cyano-4-carboxymethylthiophene-5-carboxylic acid strontium salt
Distrontium renelate
5-[Bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid, strontium salt
Ranelic Acid Strontium Salt
雷尼酸锶

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

包装

10, 50 mg in glass bottle

生化/生理作用

Strontium ranelate is a dual action bone agent (DABA). It inhibits bone resorption and stimulates bone formation, inhibiting osteoclast differentiation while activating gene expression in osteoblasts. While its exact mechanism of action is unknown, one hypothesis is that both anabolic and anti-catabolic activities may involve antagonizing nuclear factor- K B (NF- K B) activation in bone cells. Strontium ranelate has been shown to inhibit the receptor activator of NF- K B ligand (RANKL)-induced nuclear translocation of NF- K B and activator protein-1. Strontium ranelate has been used clinically for the treatment of osteoporosis and a recent multinational study indicates the drug can also be used to treat osteoarthritis.

特点和优势

This compound is featured on the Cytokine Receptors (Tumor Necrosis Receptor Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₂H₆N₂O₈SSr₂
分子量	513.49
NACRES	NA.77

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 1 mg/mL, clear (warmed)
储存温度	?20℃

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332
预防措施声明	P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable