SIB 1893

半岛bd体育手机客户端 说明

应用

SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies.

包装

10 mg in ampule

生化/生理作用

SIB 1893 non-competitively inhibits glutamate-induced increase in Ca²⁺at human metabotropic glutamate receptor 1 (hmGluR1).¹It also acts as a positive allosteric modulator of hmGluR4.²
Selective and noncompetitive mGlu₅metabotropic glutamate receptor antagonist.

特点和优势

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C14H13N
分子量	195.26
MDL编号	MFCD02262120
PubChem化学物质编号	24278718
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	>99%
形式	solid
溶解性	DMSO: 18 mg/mL
储存温度	2-8℃
SMILES string	Cc1cccc(\C=C\c2ccccc2)n1
InChI	1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
InChI key	SISOFUCTXZKSOQ-ZHACJKMWSA-N
Gene Information	human ... GRM1(2911), GRM5(2915)

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves