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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-ACTN4 antibody produced in mouse

Monoclonal Anti-ACTN4 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1403521
规格纯度
clone 4D10, ascites fluid
价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Monoclonal Anti-ACTN4 antibody produced in mouse
FSGS1
ACTININ-4
FSGS
DKFZp686K23158
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. (provided by RefSeq)

免疫原

ACTN4 (NP_004915, 592 a.a. ~ 701 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
KEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYK

外形

Clear solution

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 ascites fluid
antibody product type primary antibodies
克隆 4D10, monoclonal
分子量 antigen ~38.21 kDa
species reactivity human, mouse, rat
technique(s) indirect ELISA: suitable
western blot: 1:500-1:1000
同位素/亚型 IgG2aκ
NCBI登记号 NM_004924
UniProt登记号 O43707
运输 dry ice
储存温度 ?20℃
Gene Information human ... ACTN4(81)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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