Anti-Tyrosinase antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

The TYR (tyrosinase) gene is mapped to human chromosome 11q14.3 and codes for a membrane glycoprotein, tyrosinase. It is ubiquitously expressed in plant and animal tissue.
Anti-Tyrosinase Antibody detects endogenous levels of total Tyrosinase protein.

免疫原

The antiserum was produced against synthesized peptide derived from human Tyrosinase.

Immunogen Range:471-520

生化/生理作用

The encoded protein, tyrosinase, is involved in melanin production by catalyzing the oxidation of L -tyrosine and L - 3, 4-dihydroxyphenylalanine to form dopaquinone. TYR (tyrosinase) is associated with the development of neural crest cell into melanocytes. Biallelic mutations in the TYR gene results in an autosomal recessive disorder, oculocutaneous albinism type 1. Loss of tyrosinase activity contributes to the severity of this disorder, in which melanin is undetectable. Abnormal expression of the gene has been observed in atypical fibroxanthoma.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 60 kDa
species reactivity	human
浓度	~1 mg/mL
technique(s)	ELISA: 1:10000 western blot: 1:500-1:1000
NCBI登记号	P14679
UniProt登记号	P14679
运输	wet ice
储存温度	?20℃
Gene Information	human ... TYR(7299)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable