Anti-ZFP36L1 Antibody

半岛bd体育手机客户端 说明

一般描述

As a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.

特异性

This antibody recognizes the C-terminus of ZFP36L1.

免疫原

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.

应用

Research Category
Neuroscience
Anti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.
Research Sub Category
Neurodegenerative Diseases

质量

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 ?g/mL of this antibody detected ZFP36L1 in 10 ?g of HeLa cell lysate.

目标描述

~38 kDa observed

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HeLa cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human
species reactivity (predicted by homology)	mouse (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), horse (based on 100% sequence homology), bovine (based on 100% sequence homology)
technique(s)	western blot: suitable
NCBI登记号	NP_001231627
UniProt登记号	Q07352
运输	wet ice
Gene Information	human ... ZFP36L1(677)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable