Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human

半岛bd体育手机客户端 说明

应用

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human can be used as a test compound for analyzing the interaction between tumor necrosis factor (TNF) and its two soluble receptors by using surface plasmon resonance (SPR) technique.

生化/生理作用

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human belongs to TNF family of receptors and mediates the metabolic effects of TNF-α. Tumor Necrosis Factor Soluble Receptor II blocks the TNF-α-induced apoptosis and hence regulates the TNF-α function. It also has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline

分析说明

The biological activity is measured by its ability to neutralize the TNF-α mediated cytotoxicity in mouse L-929 cells in the presence of the metabolic inhibitor actinomycin D.

基本信息

MDL编号	MFCD02689206
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	200
生物来源	human
重组	expressed in NSO cells
测定	>95% (SDS-PAGE)
形式	lyophilized powder
效能	0.004-0.016 mg per mL ED50
分子量	52.6 kDa
包装	pkg of 50 μg
储存条件	avoid repeated freeze/thaw cycles
technique(s)	cell culture | mammalian: suitable
杂质	endotoxin, tested
UniProt登记号	P20333
储存温度	?20℃
Gene Information	human ... TNFRSF1B(7133)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable