半岛bd体育手机客户端 说明
一般描述
Rin/Rit2 (Ras-like without CAAX 2) belongs to the Ras superfamily of small guanosine triphosphatases. In human, it is expressed in several neurons whereas in mouse, it is expressed in the ganglion cell layer and inner nuclear layer of the retina. It is located on human chromosome 18q12.3.
免疫原
recombinant human Rin.
生化/生理作用
Aberrations in Rin/Rit2 (Ras-like without CAAX 2) causes parkinson′s disease. It participates in neurotrophin signaling. It trigger ERK (extracellular signal-regulated kinase) and p38 MAP (mitogen-activated protein) kinase signaling to promote differentiation.
外形
Solution in 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, and 3 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 18G4(27G2), monoclonal |
| 形式 | buffered aqueous glycerol solution |
| 分子量 | antigen ~36 kDa |
| species reactivity | human, mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | western blot: 1:5,000 using HEK293 cells expressing HA-tagged Rit |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | Q99578 |
| 运输 | wet ice |
| 储存温度 | ?20℃ |
| Gene Information | human ... RIT2(6014) mouse ... Rit2(19762) |
Sigma-Aldrich
m.cnreagent.com
