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位置: 首页> 品牌> Sigma-Aldrich> Anti-Syndecan-1 Antibody

Anti-Syndecan-1 Antibody

品牌
Sigma-Aldrich
货号
AB8230
规格纯度
serum, from rabbit
价格
6190.47 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Syndecan-1 Antibody
CD138 antigen, heparan sulfate proteoglycan fibroblast growth factor

receptor, syndecan 1, syndecan proteoglycan 1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Syndecan-1, also known as CD138, is a transmembrane (Type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization. Bearing properties of both heparan sulfate and chondroitin sulfate, Syndecan-1 functions as a cell surface proteoglycan membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types.

特异性

Reactivity with other species has not been tested.
Predicted to cross react with human, based on 100% sequence homology.
Cat. No. AB8230 recognizes mouse Syndecan-1.

免疫原

His-tagged, full-length human recombinant Syndecan-1 protein.

应用

Research Category
Cell Structure
Anti-Syndecan-1 Antibody is an antibody against Syndecan-1 for use in WB.
Research Sub Category
ECM Proteins

质量

Evaluated on a representative lot by Western blot on mouse liver lysate using 1:1000 dilution of Anti-Syndecan-1.

目标描述

The expected molecular weight of monomeric Syndecan-1 is ~32 kDa; however, the core protein often migrates as an SDS-stable dimer with an approximate M.W. of 77 kDa Additionally, a high M.W. form of the protein may often be seen between 500-1000 kDa, likely the mature form of Syndecan-1, with all of its heparan and chondroitin sulfate additions. In whole tissues, this mature form often binds tightly to ECM molecules and may require solublization by urea extraction for additional SDS-PAGE analysis (Wilsie, 2006). Triton X-100 or similar mild detergents are sufficient to release the immature precursor forms of Syndecan-1.

外形

Rabbit serum containing 0.05% NaN3.

储存及稳定性

Maintain at -20°C for up to 1 year from date of receipt.

分析说明

Control
Mouse liver lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 serum
antibody product type primary antibodies
克隆 polyclonal
species reactivity human, mouse
technique(s) western blot: suitable
NCBI登记号 NM_001006946.1
UniProt登记号 P18827
运输 wet ice

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1

Sigma-Aldrich

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