Src human

半岛bd体育手机客户端 说明

一般描述

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) belongs to the family of non-receptor tyrosine kinases. It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. The gene encoding this protein is localized on human chromosome 20q11.23.

应用

Human Src has been used to study the kinetics of Src entrapped in a series of different sol-gel derived materials.

生化/生理作用

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) phosphorylates membrane proteins and nucleoproteins and activates various intracellular signaling cascades. It has been associated with a number of human malignancies and cancers.

单位定义

One unit will phosphorylate one nmole of poly(Gly:Tyr) 4:1 per minute at pH 7.5 at 30℃.

外形

Solution in 50 mM Tris pH 7.5, 0.05 mM EDTA, 1 mM DTT, 100 mM NaCl, 0.05% NP-40, and 50% glycerol.

基本信息

MDL编号	MFCD03458574
NACRES	NA.32

半岛bd体育手机客户端 性质

质量水平	200
重组	expressed in baculovirus infected insect cells
测定	≥80% (SDS-PAGE)
形式	buffered aqueous glycerol solution
分子量	60 kDa
浓度	~0.58 mg/mL protein (Bradford assay)
UniProt登记号	P12931
application(s)	cell analysis
运输	dry ice
储存温度	?70℃
Gene Information	human ... SRC(6714)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable