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FGFR4 (460-end), active, GST tagged human

品牌
Sigma-Aldrich
货号
SRP5031
规格纯度
PRECISIO?Kinase, recombinant, expressed in baculovirus infectedSf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution
价格
6113.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
FGFR4 (460-end), active, GST tagged human
CD334
MGC20292
JTK2
TKF
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

FGFR4 is a member of the fibroblast growth factor receptor family which play a role in mitogenesis and differentiation. FGFR4 preferentially binds acidic fibroblast growth factor and is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. FGFR4 gene expression is up-regulated in doxorubicin-treated, apoptosis-resistant cancer cell clones. Ectopic expression of FGFR4 in cancer cells leads to reduced apoptosis sensitivity on treatment with doxorubicin or cyclophosphamide, whereas knockdown of endogenous FGFR4 expression in breast cancer cell lines has the opposite effect.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.32

半岛bd体育手机客户端 性质

重组 expressed in baculovirus infectedSf9 cells
半岛bd体育手机客户端 线 PRECISIO?Kinase
测定 ≥80% (SDS-PAGE)
形式 buffered aqueous glycerol solution
specific activity 64-88 nmol/min·mg
分子量 ~65 kDa
NCBI登记号 NM_002011
运输 dry ice
储存温度 ?70℃
Gene Information human ... FGFR4(2264)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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